Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | BUB1 | O43683 | 1/20 | 0.39 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | HCK | P08631 | 2/20 | 0.35 |
| ▸ | SRC | P12931 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.35 |
| ▸ | MTOR | P42345 | 2/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.35 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.35 |
| ▸ | PRKDC | P78527 | 2/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31355592 | 0.81 | ACLY (0.39) | ACLYBUB1TNK2HSP90AA1HSP90AB1 | |
| SCHEMBL30500251 | 0.80 | ACLY (0.38) | ACLYBUB1TNK2HSP90AA1HSP90AB1 | |
| SCHEMBL21565885 | 0.80 | ACLY (0.38) | ACLYBUB1TNK2HSP90AA1HSP90AB1 | |
| SCHEMBL19100224 | 0.79 | ACLY (0.37) | ACLYBUB1TNK2HSP90AA1HSP90AB1 | |
| SCHEMBL24820321 | 0.76 | ACLY (0.47) | ACLYBUB1TNK2HSP90AA1HSP90AB1 | |
| SCHEMBL30792069 | 0.76 | ACLY (0.47) | ACLYBUB1TNK2HSP90AA1HSP90AB1 | |
| SCHEMBL4779283 | 0.74 | GPR119 (0.38) | ACLYBUB1TNK2HSP90AA1HSP90AB1 | |
| SCHEMBL16339898 | 0.72 | ACLY (0.54) | ACLYBUB1HSP90AA1HSP90AB1GPR119 | |
| SCHEMBL24112566 | 0.71 | ACLY (0.48) | ACLYBUB1HSP90AA1HSP90AB1GPR119 | |
| SCHEMBL30310460 | 0.71 | ACLY (0.48) | ACLYBUB1HSP90AA1HSP90AB1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119330941-A | Antitumor compounds as UPR agonists and uses thereof | 南京圣和药业股份有限公司 | 2025-01-21 | — | — | CN | disclosed |