Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | ACLY | P53396 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | HCK | P08631 | 2/20 | 0.36 |
| ▸ | SRC | P12931 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.36 |
| ▸ | MTOR | P42345 | 2/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.36 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.36 |
| ▸ | PRKDC | P78527 | 2/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.36 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | BUB1 | O43683 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31355592 | 0.76 | ACLY (0.39) | GPR119ACLYPIK3CAPIK3CDABL1 | |
| SCHEMBL21565885 | 0.75 | ACLY (0.38) | GPR119ACLYPIK3CAPIK3CDABL1 | |
| SCHEMBL30500251 | 0.75 | ACLY (0.38) | GPR119ACLYPIK3CAPIK3CDABL1 | |
| SCHEMBL19100224 | 0.74 | ACLY (0.37) | GPR119ACLYPIK3CAPIK3CDABL1 | |
| SCHEMBL31355587 | 0.74 | ACLY (0.39) | GPR119ACLYPIK3CAPIK3CDABL1 | |
| SCHEMBL18437152 | 0.68 | PIK3CD (0.38) | GPR119PIK3CAPIK3CDABL1EGFR | |
| SCHEMBL14164212 | 0.67 | GPR119 (0.48) | GPR119PIK3CAPIK3CGKDM4EMAP3K5 | |
| SCHEMBL1349273 | 0.66 | ACLY (0.47) | GPR119ACLYPIK3CAPIK3CDABL1 | |
| SCHEMBL30711258 | 0.66 | ACLY (0.47) | GPR119ACLYPIK3CAPIK3CDABL1 | |
| SCHEMBL31440156 | 0.66 | HSP90AA1 (0.39) | GPR119ACLYPIK3CAPIK3CDABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008022467-A1 | 2-SUBSTITUTED AZAIN DOLES AND 2 SUBSTITUTED THIENOPYRROLES, THEIR PRECURSORS AND NOVEL PROCESSES FOR THE PREPARATION THEREOF | LAUTENS MARK (CA) | 2008-02-28 | — | — | WO | disclosed |