Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 11/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 10/20 | 0.50 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | DOCK5 | Q9H7D0 | 1/20 | 0.37 |
| ▸ | CXCR3 | P49682 | 4/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31356018 | 0.89 | CRBN (0.42) | CRBNDDB1IKZF3DOCK5CXCR3 | |
| SCHEMBL31356129 | 0.89 | DDB1 (0.53) | CRBNDDB1 | |
| SCHEMBL31355775 | 0.87 | CRBN (0.49) | CRBNDDB1IKZF3L3MBTL1GAA | |
| SCHEMBL31356119 | 0.84 | MAPT (0.49) | CRBNDDB1 | |
| SCHEMBL31355770 | 0.82 | DDB1 (0.46) | CRBNDDB1 | |
| SCHEMBL31356194 | 0.82 | DDB1 (0.46) | CRBNDDB1 | |
| SCHEMBL31355804 | 0.80 | CRBN (0.55) | CRBNDDB1IKZF3CXCR3JAK2 | |
| SCHEMBL31355762 | 0.79 | DDB1 (0.44) | CRBNDDB1 | |
| SCHEMBL31356243 | 0.79 | CRBN (0.62) | CRBNDDB1IKZF3 | |
| SCHEMBL31356168 | 0.78 | DDB1 (0.43) | CRBNDDB1L3MBTL1GAACXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025026422-A1 | ARYL OR HETEROARYL SUBSTITUTED GLUTARIMIDE DERIVATIVE AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2025-02-06 | — | — | WO | claimed |