SCHEMBL31356018

SCHEMBL31356018

O=C1CCN(c2cccc(NCc3ccc(CN4CCC(F)(F)CC4)c(F)c3)c2)C(=O)N1

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 9/20 0.42
▸ DDB1 Q16531 8/20 0.42
▸ CXCR3 P49682 1/20 0.34
▸ METAP2 P50579 4/20 0.34
▸ MCHR1 Q99705 3/20 0.33
▸ IKZF3 Q9UKT9 1/20 0.33
▸ DOCK5 Q9H7D0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31355762 0.91 DDB1 (0.44) CRBNDDB1
SCHEMBL31356168 0.90 DDB1 (0.43) CRBNDDB1CXCR3METAP2MCHR1
SCHEMBL31355868 0.89 CRBN (0.50) CRBNDDB1CXCR3IKZF3DOCK5
SCHEMBL31356109 0.83 CRBN (0.46) CRBNDDB1CXCR3IKZF3
SCHEMBL31355755 0.83 DDB1 (0.42) CRBNDDB1
SCHEMBL31355766 0.81 CRBN (0.54) CRBNDDB1IKZF3
SCHEMBL31356252 0.80 DDB1 (0.44) CRBNDDB1
SCHEMBL31356129 0.78 DDB1 (0.53) CRBNDDB1
SCHEMBL31355770 0.78 DDB1 (0.46) CRBNDDB1
SCHEMBL31355775 0.77 CRBN (0.49) CRBNDDB1CXCR3IKZF3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025026422-A1 ARYL OR HETEROARYL SUBSTITUTED GLUTARIMIDE DERIVATIVE AND USE THEREOF 标新生物医药科技(上海)有限公司 2025-02-06 — — WO claimed
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