SCHEMBL31356129

SCHEMBL31356129

O=C1CCN(c2cccc(NCc3ccc(CN4CCCCC4)cc3)c2)C(=O)N1

nearest known ligand 0.53

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 9/20 0.53
▸ CRBN Q96SW2 9/20 0.53
▸ HRH3 Q9Y5N1 5/20 0.45
▸ HDAC4 P56524 2/20 0.40
▸ MEF2D Q14814 2/20 0.40
▸ CYP2D6 P10635 1/20 0.40
▸ CYP2C19 P33261 1/20 0.40
▸ CACNA1B Q00975 1/20 0.39
▸ NCF1 P14598 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31355868 0.89 CRBN (0.50) DDB1CRBN
SCHEMBL31355762 0.88 DDB1 (0.44) DDB1CRBNHDAC4MEF2DCACNA1B
SCHEMBL31356137 0.86 DDB1 (0.52) DDB1CRBNHRH3NCF1
SCHEMBL31356263 0.83 RAB9A (0.52) DDB1CRBNHRH3
SCHEMBL31355846 0.80 DDB1 (0.48) DDB1CRBN
SCHEMBL31355968 0.80 DDB1 (0.48) DDB1CRBN
SCHEMBL31355960 0.80 DDB1 (0.48) DDB1CRBN
SCHEMBL31356198 0.79 DDB1 (0.46) DDB1CRBNHDAC4MEF2D
SCHEMBL31356191 0.78 DDB1 (0.58) DDB1CRBNHRH3CACNA1B
SCHEMBL31356182 0.77 DDB1 (0.77) DDB1CRBNHRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025026422-A1 ARYL OR HETEROARYL SUBSTITUTED GLUTARIMIDE DERIVATIVE AND USE THEREOF 标新生物医药科技(上海)有限公司 2025-02-06 — — WO claimed
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