Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 15/20 | 0.53 |
| ▸ | DDB1 | Q16531 | 13/20 | 0.53 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.50 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31356148 | 0.89 | CRBN (0.55) | CRBNDDB1GSPT1POLBHIF1A | |
| SCHEMBL31355804 | 0.89 | CRBN (0.55) | CRBNDDB1GSPT1IKZF3 | |
| SCHEMBL31355881 | 0.88 | CRBN (0.44) | CRBNDDB1GSPT1IKZF3POLB | |
| SCHEMBL31356120 | 0.87 | CRBN (0.54) | CRBNDDB1IKZF3 | |
| SCHEMBL31355898 | 0.84 | DDB1 (0.50) | CRBNDDB1GSPT1HIF1AEPAS1 | |
| SCHEMBL31356051 | 0.82 | CRBN (0.41) | CRBNDDB1GSPT1IKZF3HIF1A | |
| SCHEMBL31356000 | 0.80 | POLB (0.45) | CRBNDDB1GSPT1POLBHRH3 | |
| SCHEMBL31355787 | 0.80 | POLB (0.45) | CRBNDDB1GSPT1POLBHRH3 | |
| SCHEMBL31355775 | 0.80 | CRBN (0.49) | CRBNDDB1IKZF3POLBHIF1A | |
| SCHEMBL31356191 | 0.78 | DDB1 (0.58) | CRBNDDB1GSPT1IKZF3HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025026422-A1 | ARYL OR HETEROARYL SUBSTITUTED GLUTARIMIDE DERIVATIVE AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2025-02-06 | — | — | WO | claimed |