Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 12/20 | 0.55 |
| ▸ | DDB1 | Q16531 | 11/20 | 0.55 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31356091 | 0.89 | CRBN (0.53) | CRBNDDB1GSPT1HRH3POLB | |
| SCHEMBL31356191 | 0.89 | DDB1 (0.58) | CRBNDDB1GSPT1HRH3 | |
| SCHEMBL31356060 | 0.86 | CRBN (0.44) | CRBNDDB1GSPT1HRH3POLB | |
| SCHEMBL31356221 | 0.85 | DDB1 (0.67) | CRBNDDB1HRH3 | |
| SCHEMBL31356173 | 0.83 | TNF (0.58) | CRBNDDB1GSPT1HIF1AEPAS1 | |
| SCHEMBL31356215 | 0.80 | DDB1 (0.44) | CRBNDDB1GSPT1HRH3 | |
| SCHEMBL25217869 | 0.79 | CRBN (0.64) | CRBNDDB1GSPT1HRH3POLB | |
| SCHEMBL31355804 | 0.79 | CRBN (0.55) | CRBNDDB1GSPT1 | |
| SCHEMBL31355967 | 0.78 | CRBN (0.45) | CRBNDDB1GSPT1HRH3POLB | |
| SCHEMBL31355862 | 0.78 | CRBN (0.45) | CRBNDDB1GSPT1HRH3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119768392-A | Aryl or heteroaryl substituted glutarimide derivatives and uses thereof | 标新生物医药科技(上海)有限公司 | 2025-04-04 | — | — | CN | claimed |
| WO-2025026422-A1 | ARYL OR HETEROARYL SUBSTITUTED GLUTARIMIDE DERIVATIVE AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2025-02-06 | — | — | WO | claimed |