Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 12/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23168951 | 1.00 | MAPT (0.40) | MAPTP2RX7GAAMEN1CYP1A2 | |
| SCHEMBL23168940 | 0.90 | MAPT (0.40) | MAPTP2RX7KMT2AKLKB1 | |
| SCHEMBL23168931 | 0.85 | NPBWR1 (0.46) | MAPT | |
| SCHEMBL23168775 | 0.85 | MAPT (0.43) | MAPTMEN1CYP1A2POLBCYP3A4 | |
| SCHEMBL24820993 | 0.84 | MKNK1 (0.42) | MAPTMEN1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL23168745 | 0.84 | KLKB1 (0.40) | ALDH1A1KLKB1 | |
| SCHEMBL23168950 | 0.84 | P2RX7 (0.40) | MAPTP2RX7GAAMEN1CYP1A2 | |
| SCHEMBL29822173 | 0.84 | P2RX7 (0.40) | MAPTP2RX7GAAMEN1CYP1A2 | |
| SCHEMBL23168928 | 0.82 | THRB (0.38) | — | |
| SCHEMBL23168751 | 0.81 | NPBWR1 (0.37) | MAPTP2RX7CYP1A2POLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114621207-B | Compound serving as thyroid hormone beta receptor agonist and application thereof | 广东东阳光药业股份有限公司 | 2025-02-11 | — | — | CN | disclosed |