Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.75 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.75 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.75 |
| ▸ | MAPT | P10636 | 8/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.68 |
| ▸ | TP53 | P04637 | 5/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | CASP1 | P29466 | 2/20 | 0.68 |
| ▸ | CASP7 | P55210 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | ACHE | P22303 | 3/20 | 0.63 |
| ▸ | BACE1 | P56817 | 3/20 | 0.63 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.58 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4650608 | 0.89 | CSNK2A2 (0.82) | CSNK2A2CSNK2BCSNK2A1MAPTKDM4E | |
| SCHEMBL4648920 | 0.86 | CSNK2A2 (1.00) | CSNK2A2CSNK2BCSNK2A1MAPTKDM4E | |
| SCHEMBL31356554 | 0.86 | CSNK2A2 (1.00) | CSNK2A2CSNK2BCSNK2A1MAPTKDM4E | |
| SCHEMBL17786466 | 0.85 | CSNK2A2 (0.75) | CSNK2A2CSNK2BCSNK2A1MAPTKDM4E | |
| SCHEMBL30807192 | 0.85 | CYP3A4 (0.85) | CSNK2A2CSNK2BCSNK2A1MAPTKDM4E | |
| SCHEMBL12941170 | 0.85 | CSNK2A2 (0.75) | CSNK2A2CSNK2BCSNK2A1MAPTKDM4E | |
| SCHEMBL7124716 | 0.84 | CSNK2A2 (0.74) | CSNK2A2CSNK2BCSNK2A1MAPTKDM4E | |
| SCHEMBL25233130 | 0.82 | ACHE (0.81) | CSNK2A2CSNK2BCSNK2A1MAPTKDM4E | |
| SCHEMBL2121813 | 0.82 | KDM4E (0.74) | CSNK2A2CSNK2BCSNK2A1MAPTKDM4E | |
| SCHEMBL15676583 | 0.82 | KDM4E (0.74) | CSNK2A2CSNK2BCSNK2A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7456288-B2 | Heterocyclic compounds and methods of making and using thereof | REDDY US THERAPEUTICS, INC. (US) | 2008-11-25 | — | — | US | disclosed |
| US-7456288-B2 | Heterocyclic compounds and methods of making and using thereof | REDDY US THERAPEUTICS, INC. (US) | 2008-11-25 | — | — | US | disclosed |
| US-7456288-B2 | Heterocyclic compounds and methods of making and using thereof | REDDY US THERAPEUTICS, INC. (US) | 2008-11-25 | — | — | US | disclosed |
| US-20050119269-A1 | Heterocyclic compounds and methods of making and using thereof | DR. REDDY'S LABORATORIES LTD. (IN) | 2005-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119269-A1 | Heterocyclic compounds and methods of making and using thereof | PYGM, MYLK, HMOX1 | CSNK2A2 1481/4885CSNK2B 1756/4885CSNK2A1 1314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.