Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30404210 | 0.80 | CYP2C19 (0.42) | POLBPKMCYP2C19LMNACYP2C9 | |
| SCHEMBL4656266 | 0.80 | CYP2C19 (0.42) | POLBPKMCYP2C19LMNACYP2C9 | |
| SCHEMBL4656264 | 0.80 | CYP2C19 (0.42) | POLBPKMCYP2C19LMNACYP2C9 | |
| SCHEMBL15902462 | 0.77 | KMT2A (0.53) | PKMCYP2C19CYP2D6LMNACYP2C9 | |
| SCHEMBL13240841 | 0.75 | ROCK2 (0.53) | CYP2D6SRCLMNAALDH1A1KDM4E | |
| SCHEMBL1695685 | 0.75 | ROCK2 (0.53) | CYP2D6SRCLMNAALDH1A1KDM4E | |
| SCHEMBL28425025 | 0.74 | CYP2C19 (0.41) | POLBPKMCYP2C19LMNACYP2C9 | |
| SCHEMBL8345196 | 0.74 | ALDH1A1 (0.45) | POLBPKMCYP2C19LMNACYP2C9 | |
| Hydrochloric Acid SCHEMBL1696178 | 0.74 | ROCK2 (0.51) | CYP2D6SRCLMNAALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL2483356 | 0.74 | ROCK2 (0.51) | CYP2D6SRCLMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111057024-B | Sydney ketone and Sydney ketimine compound, and preparation method and application thereof | 华东理工大学 | 2025-02-07 | — | — | CN | disclosed |