Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4656266 | 1.00 | CYP2C19 (0.42) | CYP2C19MEN1GAAKMT2AHSD17B10 | |
| SCHEMBL30404210 | 1.00 | CYP2C19 (0.42) | CYP2C19MEN1GAAKMT2AHSD17B10 | |
| SCHEMBL8345196 | 0.83 | ALDH1A1 (0.45) | CYP2C19MEN1GAAKMT2AHSD17B10 | |
| SCHEMBL31357263 | 0.80 | POLB (0.41) | CYP2C19ALDH1A1CYP2C9HPGDLMNA | |
| SCHEMBL28425025 | 0.80 | CYP2C19 (0.41) | CYP2C19MEN1GAAKMT2AHSD17B10 | |
| SCHEMBL7775515 | 0.79 | CYP2C19 (0.40) | CYP2C19MEN1GAAKMT2AHSD17B10 | |
| SCHEMBL7775511 | 0.79 | CYP2C19 (0.40) | CYP2C19MEN1GAAKMT2AHSD17B10 | |
| SCHEMBL28289230 | 0.78 | HSD17B10 (0.35) | MEN1GAAKMT2AHSD17B10ALDH1A1 | |
| SCHEMBL3836356 | 0.77 | ALOX5 (0.47) | CYP2C19MEN1GAAKMT2AHSD17B10 | |
| SCHEMBL28264681 | 0.77 | CYP2C19 (0.39) | CYP2C19MEN1GAAKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160244484-A1 | ANTI-INFLAMMATORY TRIPEPTIDES | DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) | 2016-08-25 | — | — | US | claimed |
| EP-3049428-A1 | ANTI-INFLAMMATORY TRIPEPTIDES | Dr. August Wolff GmbH & Co. KG Arzneimittel (DE) | 2016-08-03 | — | — | EP | claimed |
| WO-2015040235-A1 | ANTI-INFLAMMATORY TRIPEPTIDES | DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) | 2015-03-26 | — | — | WO | claimed |
| EP-1006122-B1 | PHENETHYLAMINE DERIVATIVES | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2008-12-03 | — | — | EP | claimed |
| US-10954269-B2 | Anti-inflammatory tripeptides | DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) | 2021-03-23 | — | — | US | disclosed |
| US-20190153029-A1 | ANTI-INFLAMMATORY TRIPEPTIDES | DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) | 2019-05-23 | — | — | US | disclosed |
| US-10227379-B2 | Anti-inflammatory tripeptides | DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) | 2019-03-12 | — | — | US | disclosed |
| US-20160244484-A1 | ANTI-INFLAMMATORY TRIPEPTIDES | DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) | 2016-08-25 | — | — | US | disclosed |
| EP-3049428-A1 | ANTI-INFLAMMATORY TRIPEPTIDES | Dr. August Wolff GmbH & Co. KG Arzneimittel (DE) | 2016-08-03 | — | — | EP | disclosed |
| WO-2015040235-A1 | ANTI-INFLAMMATORY TRIPEPTIDES | DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) | 2015-03-26 | — | — | WO | disclosed |
| EP-1006122-B1 | PHENETHYLAMINE DERIVATIVES | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2008-12-03 | — | — | EP | disclosed |
| US-6255285-B1 | GASTROINTESTINAL DISORDERS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-07-03 | — | — | US | disclosed |
| CN-1272114-A | Phenethylamine derivatives | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2000-11-01 | — | — | CN | disclosed |
| EP-1006122-A1 | PHENETHYLAMINE DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2000-06-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160244484-A1 | ANTI-INFLAMMATORY TRIPEPTIDES | VIP, TNF, ENPEP | CYP2C19 2488/4885MEN1 3418/4885GAA 1765/4885 |
| US-20190153029-A1 | ANTI-INFLAMMATORY TRIPEPTIDES | VIP, TNF, ENPEP | CYP2C19 2488/4885MEN1 3418/4885GAA 1765/4885 |
| US-10954269-B2 | Anti-inflammatory tripeptides | VIP, TNF, ENPEP | CYP2C19 2488/4885MEN1 3418/4885GAA 1765/4885 |
| US-10227379-B2 | Anti-inflammatory tripeptides | VIP, TNF, ENPEP | CYP2C19 2488/4885MEN1 3418/4885GAA 1765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.