Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 4/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | LHCGR | P22888 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | GLS | O94925 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31357637 | 1.00 | BACE1 (0.34) | BACE1DGAT1CNR2ACACBCYP1A2 | |
| SCHEMBL23595100 | 1.00 | BACE1 (0.34) | BACE1DGAT1CNR2ACACBCYP1A2 | |
| SCHEMBL28809474 | 0.89 | CNR2 (0.37) | DGAT1CNR2ACACBCYP1A2CYP3A4 | |
| SCHEMBL31357651 | 0.89 | CNR2 (0.37) | DGAT1CNR2ACACBCYP1A2CYP3A4 | |
| SCHEMBL23595147 | 0.88 | PLAU (0.36) | BACE1DGAT1 | |
| SCHEMBL31357691 | 0.88 | PLAU (0.36) | BACE1DGAT1 | |
| SCHEMBL31357614 | 0.88 | PLAU (0.36) | BACE1DGAT1 | |
| SCHEMBL23582366 | 0.86 | FFAR1 (0.37) | CNR2CYP2C9FFAR1NOS3NOS1 | |
| SCHEMBL23582072 | 0.83 | ASIC3 (0.40) | BACE1CNR2ACACBCYP1A2CYP3A4 | |
| SCHEMBL29438253 | 0.83 | ASIC3 (0.40) | BACE1CNR2ACACBCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114846013-B | Novel aminoaryl derivatives useful as diacylglycerol acyltransferase 2 inhibitors and uses thereof | 株式会社LG化学 | 2024-12-20 | — | — | CN | disclosed |