Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 3/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.33 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 2/20 | 0.33 |
| ▸ | ACACB | O00763 | 2/20 | 0.33 |
| ▸ | ACACA | Q13085 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | CKS1B | P61024 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31357651 | 1.00 | CNR2 (0.37) | CNR2CNR1TRPV1BRD4CTSB | |
| SCHEMBL23595100 | 0.89 | BACE1 (0.34) | CNR2CNR1BRD4CTSBCTSS | |
| SCHEMBL31357637 | 0.89 | BACE1 (0.34) | CNR2CNR1BRD4CTSBCTSS | |
| SCHEMBL31357656 | 0.89 | BACE1 (0.34) | CNR2CNR1BRD4CTSBCTSS | |
| SCHEMBL31357705 | 0.88 | CTSL (0.35) | TRPV1CTSBCTSSCTSKDGAT1 | |
| SCHEMBL28809392 | 0.88 | CTSL (0.35) | TRPV1CTSBCTSSCTSKDGAT1 | |
| SCHEMBL23582476 | 0.86 | SHMT1 (0.40) | CNR2CNR1SHMT1SHMT2CYP2C9 | |
| SCHEMBL18425126 | 0.78 | ABCG2 (0.41) | CNR2CNR1TRPV1 | |
| SCHEMBL31357683 | 0.78 | BRAF (0.37) | CNR2CTSBCTSSCTSKACACB | |
| SCHEMBL31357692 | 0.78 | BRAF (0.37) | CNR2CTSBCTSSCTSKACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114846013-B | Novel aminoaryl derivatives useful as diacylglycerol acyltransferase 2 inhibitors and uses thereof | 株式会社LG化学 | 2024-12-20 | — | — | CN | disclosed |
| CN-114846013-A | Novel aminoaryl derivatives useful as diacylglycerol acyltransferase 2 inhibitors and uses thereof | 株式会社LG化学 | 2022-08-02 | — | — | CN | disclosed |