Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | DTYMK | P23919 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31358013 | 0.85 | KDM1A (0.38) | DGAT2ESR2NR1H2 | |
| SCHEMBL31358074 | 0.83 | DGAT2 (0.39) | MAPK1PDK4DGAT2GPR119ESR2 | |
| SCHEMBL31358097 | 0.83 | IRAK4 (0.41) | DGAT2GPR119ALK | |
| SCHEMBL31358040 | 0.83 | ALDH2 (0.42) | DGAT2GPR119ESR2ALK | |
| SCHEMBL13584241 | 0.82 | PDK4 (0.59) | PDK4HTR6NAMPT | |
| SCHEMBL31358092 | 0.81 | DGAT2 (0.40) | MAPK1PDK4DGAT2CHRM2CHRM4 | |
| SCHEMBL22944326 | 0.81 | PDK4 (0.48) | MAPK1PDK4DGAT2CHRM2CHRM4 | |
| SCHEMBL31357947 | 0.81 | NAMPT (0.38) | MAPK1PDK4CHRM2CHRM4CHRM1 | |
| SCHEMBL31357889 | 0.79 | DGAT2 (0.38) | MAPK1PDK4DGAT2HTR6GPR119 | |
| SCHEMBL3642252 | 0.78 | PDK4 (0.47) | MAPK1PDK4DGAT2GPR119ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024259241-A1 | 5-HT2A RECEPTOR MODULATORS AND METHODS OF USE THEREOF | Transneural Therapeutics, Inc. (US) | 2024-12-19 | — | — | WO | disclosed |