Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 8/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 6/20 | 0.38 |
| ▸ | WDR5 | P61964 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31358040 | 0.85 | ALDH2 (0.42) | DGAT2ESR2ALDH2 | |
| SCHEMBL31357908 | 0.85 | MAPK1 (0.41) | DGAT2ESR2NR1H2 | |
| SCHEMBL31357996 | 0.82 | WDR5 (0.39) | DGAT2CDK9CCNT1WDR5ESR2 | |
| SCHEMBL31357889 | 0.82 | DGAT2 (0.38) | DGAT2CDK9CCNT1WDR5ESR2 | |
| SCHEMBL31287991 | 0.81 | KDM1A (0.41) | KDM1ACDK9CCNT1ESR2NR1H2 | |
| SCHEMBL31358058 | 0.80 | DGAT2 (0.40) | DGAT2CDK9CCNT1WDR5ESR2 | |
| SCHEMBL31358074 | 0.80 | DGAT2 (0.39) | KDM1ADGAT2CDK9CCNT1WDR5 | |
| SCHEMBL31358097 | 0.79 | IRAK4 (0.41) | DGAT2ALDH2 | |
| SCHEMBL3642252 | 0.74 | PDK4 (0.47) | DGAT2CDK9CCNT1WDR5ESR2 | |
| SCHEMBL31357884 | 0.74 | DGAT2 (0.40) | DGAT2WDR5ESR2NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024259241-A1 | 5-HT2A RECEPTOR MODULATORS AND METHODS OF USE THEREOF | Transneural Therapeutics, Inc. (US) | 2024-12-19 | — | — | WO | disclosed |