Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | EED | O75530 | 1/20 | 0.36 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.36 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.36 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.36 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31357915 | 0.82 | TBK1 (0.38) | DGAT2GPR119RORCEEDRBBP4 | |
| SCHEMBL31357908 | 0.81 | MAPK1 (0.41) | DGAT2GPR119PDK4MAPK1NR1H2 | |
| SCHEMBL31358018 | 0.80 | TBK1 (0.38) | DGAT2GPR119RORCEEDRBBP4 | |
| SCHEMBL31357889 | 0.79 | DGAT2 (0.38) | DGAT2GPR119PDK4MAPK1NR1H2 | |
| SCHEMBL31358097 | 0.79 | IRAK4 (0.41) | DGAT2GPR119RORC | |
| SCHEMBL31358040 | 0.79 | ALDH2 (0.42) | DGAT2GPR119RORCESR2 | |
| SCHEMBL31287977 | 0.77 | RORC (0.42) | DGAT2GPR119RORCPDK4EED | |
| SCHEMBL31357996 | 0.75 | WDR5 (0.39) | DGAT2GPR119PDK4NR1H2ESR2 | |
| SCHEMBL22944326 | 0.75 | PDK4 (0.48) | DGAT2GPR119PDK4MAPK1NR1H2 | |
| SCHEMBL31358013 | 0.73 | KDM1A (0.38) | DGAT2NR1H2ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024259241-A1 | 5-HT2A RECEPTOR MODULATORS AND METHODS OF USE THEREOF | Transneural Therapeutics, Inc. (US) | 2024-12-19 | — | — | WO | disclosed |