Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 5/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.35 |
| ▸ | CDK9 | P50750 | 2/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.34 |
| ▸ | EED | O75530 | 1/20 | 0.33 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.33 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.33 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31358018 | 0.90 | TBK1 (0.38) | TBK1RORCGPR119NR1H2DGAT2 | |
| SCHEMBL31358092 | 0.82 | DGAT2 (0.40) | TBK1RORCGPR119NR1H2DGAT2 | |
| SCHEMBL15595098 | 0.74 | PDK4 (0.47) | GPR119CCNT1CDK9NR1H2PDE4B | |
| SCHEMBL31357884 | 0.74 | DGAT2 (0.40) | GPR119NR1H2DGAT2 | |
| SCHEMBL31358097 | 0.73 | IRAK4 (0.41) | RORCGPR119DGAT2 | |
| SCHEMBL31358040 | 0.73 | ALDH2 (0.42) | RORCGPR119DGAT2 | |
| SCHEMBL31357877 | 0.73 | JAK1 (0.30) | — | |
| SCHEMBL25953613 | 0.72 | PDE4B (0.41) | GPR119NR1H2PDE4BPTGDR2NSD2 | |
| SCHEMBL31357889 | 0.71 | DGAT2 (0.38) | GPR119CCNT1CDK9NR1H2DGAT2 | |
| SCHEMBL31358074 | 0.71 | DGAT2 (0.39) | GPR119CCNT1CDK9NR1H2DGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024259241-A1 | 5-HT2A RECEPTOR MODULATORS AND METHODS OF USE THEREOF | Transneural Therapeutics, Inc. (US) | 2024-12-19 | — | — | WO | disclosed |