Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | MARK3 | P27448 | 1/20 | 0.48 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.48 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.48 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.48 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | PRKCG | P05129 | 1/20 | 0.41 |
| ▸ | PRKCB | P05771 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | PRKCH | P24723 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22944326 | 0.81 | PDK4 (0.48) | HTR6ACHECHRM2CHRM4CHRM1 | |
| SCHEMBL27201656 | 0.78 | PDK4 (0.47) | CHRM2CHRM4CHRM1CHRM3MAPK1 | |
| SCHEMBL3642252 | 0.78 | PDK4 (0.47) | MAPK1PDK4DGAT2 | |
| SCHEMBL31357908 | 0.78 | MAPK1 (0.41) | HTR6CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL27201485 | 0.78 | MAPK1 (0.44) | HTR6L3MBTL1MAPK1DGAT2 | |
| SCHEMBL31358261 | 0.78 | DTYMK (0.44) | HTR6CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL31357883 | 0.77 | DGAT2 (0.42) | HTR6MAPK1PDK4DGAT2MEN1 | |
| SCHEMBL6352947 | 0.77 | MAPK1 (0.49) | MAPK1PDK4 | |
| SCHEMBL15595098 | 0.77 | PDK4 (0.47) | MAPK1PDK4DGAT2MEN1KMT2A | |
| SCHEMBL29806197 | 0.75 | HSP90AA1 (0.44) | MAPK1PDK4DGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024259241-A1 | 5-HT2A RECEPTOR MODULATORS AND METHODS OF USE THEREOF | Transneural Therapeutics, Inc. (US) | 2024-12-19 | — | — | WO | disclosed |