Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | DRD4 | P21917 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31357965 | 1.00 | KCNH2 (0.56) | KCNH2HDAC1ADRA1DKDM4ELMNA | |
| SCHEMBL31358076 | 1.00 | KCNH2 (0.56) | KCNH2HDAC1ADRA1DKDM4ELMNA | |
| SCHEMBL31357989 | 0.84 | OPRL1 (0.60) | KCNH2HDAC1DRD2DRD4DRD3 | |
| SCHEMBL22619183 | 0.80 | DRD2 (0.65) | KDM4ELMNAHTTMAPK1ATM | |
| SCHEMBL31358186 | 0.78 | IDO1 (0.52) | KCNH2KDM4ELMNAHTTMAPK1 | |
| SCHEMBL31357973 | 0.78 | IDO1 (0.52) | KCNH2KDM4ELMNAHTTMAPK1 | |
| SCHEMBL31358145 | 0.78 | IDO1 (0.52) | KCNH2KDM4ELMNAHTTMAPK1 | |
| SCHEMBL22619180 | 0.77 | DRD2 (0.61) | KDM4ELMNAHTTMAPK1CYP2D6 | |
| Hydrochloric Acid SCHEMBL11230694 | 0.76 | KDM4E (0.60) | KCNH2HDAC1ADRA1DKDM4EATM | |
| Hydrochloric Acid SCHEMBL7259012 | 0.76 | ADRA1D (0.82) | ADRA1DKDM4EATMCYP2D6HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024259241-A1 | 5-HT2A RECEPTOR MODULATORS AND METHODS OF USE THEREOF | Transneural Therapeutics, Inc. (US) | 2024-12-19 | — | — | WO | disclosed |