Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | MPO | P05164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31357973 | 1.00 | IDO1 (0.52) | IDO1MPOKDM4ETSHRRECQL | |
| SCHEMBL31358186 | 1.00 | IDO1 (0.52) | IDO1MPOKDM4ETSHRRECQL | |
| SCHEMBL31357965 | 0.78 | KCNH2 (0.56) | KDM4EDRD2KCNH2LMNAHTT | |
| SCHEMBL31358076 | 0.78 | KCNH2 (0.56) | KDM4EDRD2KCNH2LMNAHTT | |
| SCHEMBL31357992 | 0.78 | KCNH2 (0.56) | KDM4EDRD2KCNH2LMNAHTT | |
| SCHEMBL9288358 | 0.76 | DRD2 (0.46) | DRD2HTR2AHTR2CKCNH2 | |
| SCHEMBL15485748 | 0.72 | KDM4E (0.47) | IDO1KDM4ETSHRHTR2AHTR2C | |
| SCHEMBL4004747 | 0.72 | RAB9A (0.48) | IDO1KDM4EHTR2AHTR2CRAB9A | |
| SCHEMBL27952106 | 0.72 | TSHR (0.68) | IDO1MPOKDM4ETSHRRECQL | |
| SCHEMBL31357989 | 0.72 | OPRL1 (0.60) | IDO1DRD2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024259241-A1 | 5-HT2A RECEPTOR MODULATORS AND METHODS OF USE THEREOF | Transneural Therapeutics, Inc. (US) | 2024-12-19 | — | — | WO | disclosed |