Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR2 | Q16832 | 7/20 | 0.53 |
| ▸ | DDR1 | Q08345 | 6/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | VNN1 | O95497 | 2/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29933875 | 0.90 | HDAC8 (0.49) | DDR2DDR1HDAC8HDAC1HDAC6 | |
| SCHEMBL28884708 | 0.90 | HDAC8 (0.49) | DDR2DDR1HDAC8HDAC1HDAC6 | |
| SCHEMBL28884674 | 0.88 | DDR1 (0.47) | DDR2DDR1HDAC8HDAC1HDAC6 | |
| SCHEMBL31359386 | 0.88 | HDAC8 (0.57) | DDR2DDR1HDAC8HDAC1HDAC6 | |
| SCHEMBL29935081 | 0.79 | DDR1 (0.44) | DDR2DDR1HDAC8HDAC1HDAC6 | |
| SCHEMBL31359341 | 0.79 | MKNK1 (0.46) | MKNK1MKNK2 | |
| SCHEMBL31359374 | 0.78 | MKNK1 (0.38) | DDR2DDR1VNN1PTK2MKNK1 | |
| SCHEMBL31359360 | 0.76 | HDAC8 (0.53) | DDR2DDR1HDAC8HDAC1HDAC6 | |
| SCHEMBL29934245 | 0.75 | HDAC1 (0.43) | DDR2DDR1HDAC8HDAC1HDAC6 | |
| SCHEMBL29934033 | 0.75 | VNN1 (0.51) | DDR2DDR1HDAC8HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119371371-A | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2025-01-28 | — | — | CN | disclosed |
| CN-115315421-B | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2024-12-03 | — | — | CN | disclosed |