SCHEMBL31359685

SCHEMBL31359685

COc1c(N)ncc2cnn(COCC[Si](C)(C)C)c12

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 4/20 0.34
ALOX5AP P20292 2/20 0.31
FEN1 P39748 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31359710 0.85 DGAT1 (0.34) DGAT1
SCHEMBL25758213 0.78 HASPIN (0.40)
SCHEMBL30498340 0.78 HASPIN (0.40)
SCHEMBL24344356 0.78 DGAT1 (0.36) DGAT1
SCHEMBL25324134 0.76 DGAT1 (0.33) DGAT1
SCHEMBL25758418 0.76 MAP3K12 (0.35)
SCHEMBL30498058 0.76 MAP3K12 (0.35)
SCHEMBL27150340 0.75 HTR2C (0.43) DGAT1
SCHEMBL30498284 0.75 DHFR (0.33)
SCHEMBL25758954 0.75 DHFR (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4727935-A1 TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF Lynk Pharmaceuticals Co. Ltd. (CN) 2026-04-22 EP disclosed
WO-2024254832-A1 TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF LYNK PHARMACEUTICALS CO. LTD. (CN) 2024-12-19 WO disclosed
WO-2024255886-A1 TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF LYNK PHARMACEUTICALS CO. LTD. (CN) 2024-12-19 WO disclosed