Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 17/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.42 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3132193 | 0.92 | SSTR5 (0.39) | SSTR5KCNH2 | |
| SCHEMBL3136054 | 0.92 | SSTR5 (0.41) | SSTR5KCNH2 | |
| SCHEMBL3138164 | 0.91 | SSTR5 (0.56) | SSTR5KCNH2SSTR3 | |
| SCHEMBL3142488 | 0.90 | SSTR5 (0.43) | SSTR5KCNH2 | |
| SCHEMBL3137220 | 0.89 | SSTR5 (0.38) | SSTR5KCNH2 | |
| SCHEMBL3130637 | 0.89 | SSTR5 (0.44) | SSTR5KCNH2 | |
| SCHEMBL3086963 | 0.88 | SSTR5 (0.51) | SSTR5KCNH2 | |
| SCHEMBL3138725 | 0.87 | MEN1 (0.39) | SSTR5KCNH2 | |
| SCHEMBL3138335 | 0.84 | ALDH1A1 (0.39) | SSTR5 | |
| SCHEMBL3138780 | 0.80 | PDE4B (0.41) | SSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2142528-B1 | 1-(1-BENZYLPIPERIDIN-4-YL)BENZIMIDAZ0LE -5-CARBOXYLIC ACID DERIVATIVES FOR THE TREATMENT OF DIABETES MELLITUS | HOFFMANN LA ROCHE (CH) | 2010-07-07 | — | — | EP | claimed |