Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GHSR | Q92847 | 9/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3098617 | 0.90 | ALDH1A1 (0.41) | ALDH1A1GHSRCHRM3CHRM2SSTR5 | |
| SCHEMBL3136029 | 0.84 | SSTR5 (0.44) | SSTR5 | |
| SCHEMBL3136054 | 0.84 | SSTR5 (0.41) | GHSRCHRM3CHRM2SSTR5 | |
| SCHEMBL3132193 | 0.84 | SSTR5 (0.39) | ALDH1A1CHRM3CHRM2SSTR5 | |
| SCHEMBL3142488 | 0.82 | SSTR5 (0.43) | ALDH1A1SSTR5 | |
| SCHEMBL3138725 | 0.81 | MEN1 (0.39) | ALDH1A1CHRM3CHRM2SSTR5 | |
| SCHEMBL3137220 | 0.81 | SSTR5 (0.38) | GHSRCHRM3CHRM2SSTR5 | |
| SCHEMBL3130637 | 0.81 | SSTR5 (0.44) | ALDH1A1CHRM3CHRM2SSTR5 | |
| SCHEMBL3138164 | 0.80 | SSTR5 (0.56) | SSTR5 | |
| SCHEMBL3138780 | 0.79 | PDE4B (0.41) | ALDH1A1CHRM3CHRM2SSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2142528-B1 | 1-(1-BENZYLPIPERIDIN-4-YL)BENZIMIDAZ0LE -5-CARBOXYLIC ACID DERIVATIVES FOR THE TREATMENT OF DIABETES MELLITUS | HOFFMANN LA ROCHE (CH) | 2010-07-07 | — | — | EP | claimed |