Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 6/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.35 |
| ▸ | BTK | Q06187 | 4/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30736122 | 0.77 | CSNK1E (0.37) | CSNK1EBTKSRC | |
| SCHEMBL31360465 | 0.74 | TGFBR1 (0.38) | TGFBR1SCN9AGRM5ADAMTS4SYK | |
| SCHEMBL29002671 | 0.74 | PARP1 (0.43) | TGFBR1GRM5ADAMTS4PPARGSYK | |
| SCHEMBL30736056 | 0.72 | EGFR (0.40) | BTK | |
| SCHEMBL25714790 | 0.69 | ADAMTS4 (0.33) | TGFBR1BTKGRM5ADAMTS4FFAR4 | |
| SCHEMBL29002685 | 0.69 | PPARG (0.42) | TGFBR1GRM5ADAMTS4PPARG | |
| SCHEMBL29002669 | 0.68 | SYK (0.42) | TGFBR1SCN9AGRM5ADAMTS4SYK | |
| SCHEMBL28981125 | 0.68 | TGFBR1 (0.41) | TGFBR1GRM5ADAMTS4PPARGSRC | |
| SCHEMBL29002666 | 0.68 | PARP1 (0.39) | TGFBR1SCN9AGRM5ADAMTS4PPARG | |
| SCHEMBL31745507 | 0.68 | GRM5 (0.35) | TGFBR1SCN9ABTKGRM5PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119451964-A | FGFR2 and FGFR3 inhibitors and uses thereof | 英矽智能科技知识产权有限公司 | 2025-02-14 | — | — | CN | disclosed |