Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 7/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 5/20 | 0.38 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29002685 | 0.89 | PPARG (0.42) | TGFBR1ADAMTS4MAPK14F2F10 | |
| SCHEMBL29002645 | 0.85 | LMNA (0.41) | ADAMTS4F10PPARG | |
| SCHEMBL28981125 | 0.82 | TGFBR1 (0.41) | TGFBR1ADAMTS4MAPK14F2F10 | |
| SCHEMBL29002666 | 0.79 | PARP1 (0.39) | PARP1CHEK2TGFBR1ADAMTS4SYK | |
| SCHEMBL30791518 | 0.75 | FNTA (0.40) | ADAMTS4F10 | |
| SCHEMBL29002669 | 0.74 | SYK (0.42) | CHEK2TGFBR1ADAMTS4SYKF2 | |
| SCHEMBL31360478 | 0.74 | CSNK1E (0.43) | TGFBR1ADAMTS4SYKPPARGGRM5 | |
| SCHEMBL31360465 | 0.73 | TGFBR1 (0.38) | TGFBR1ADAMTS4SYKF2F10 | |
| SCHEMBL29002662 | 0.71 | ALDH1A1 (0.43) | ADAMTS4F10 | |
| SCHEMBL25716096 | 0.70 | TEK (0.53) | CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115772161-A | Nitrogen-containing heteroaryl compound, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2023-03-10 | — | — | CN | disclosed |