Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GRN | P28799 | 1/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | TET3 | O43151 | 1/20 | 0.31 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.31 |
| ▸ | ESRRB | O95718 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13329286 | 0.91 | ALDH1A1 (0.39) | MMEALDH1A1GRNSORT1KMT2A | |
| SCHEMBL4144659 | 0.87 | ALDH1A1 (0.36) | MMEALDH1A1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL9290922 | 0.81 | TET2 (0.39) | ALDH1A1GRNSORT1SMN1; SMN2TGFBR1 | |
| SCHEMBL13941536 | 0.81 | MME (0.38) | MMEALDH1A1KMT2ASMN1; SMN2PPARG | |
| SCHEMBL7707105 | 0.79 | MME (0.42) | MMEKMT2ASMN1; SMN2TSHRPPARG | |
| SCHEMBL4144935 | 0.77 | GRN (0.36) | ALDH1A1GRNSORT1SMN1; SMN2TGFBR1 | |
| SCHEMBL14870828 | 0.76 | ESRRB (0.41) | ALDH1A1KMT2ASMN1; SMN2TSHRCA1 | |
| SCHEMBL26625811 | 0.76 | ESRRB (0.41) | ALDH1A1KMT2ASMN1; SMN2TSHRCA1 | |
| SCHEMBL7046871 | 0.75 | KMT2A (0.44) | MMEALDH1A1GRNSORT1KMT2A | |
| SCHEMBL27351667 | 0.75 | MME (0.42) | MMEKMT2ASMN1; SMN2TGFBR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079528-B1 | USE IN PERFUMERY AND FLAVOURING AND PROCESS FOR THE PREPARATION OF 5,5-DIMETHYL-3-ETHYL-3,4-DIHYDROFURAN-2-ONE | MANE FILS V (FR) | 2010-07-21 | — | — | EP | disclosed |
| CN-101583399-A | Use in perfumery and flavouring and process for the preparation of 5,5-dimethyl-3-ethyl-3,4-dihydrofuran-2-one | MANE FILS V (FR) | 2009-11-18 | — | — | CN | disclosed |
| EP-2079528-A2 | USE IN PERFUMERY AND FLAVOURING AND PROCESS FOR THE PREPARATION OF 5,5-DIMETHYL-3-ETHYL-3,4-DIHYDROFURAN-2-ONE | V. Mane Fils (FR) | 2009-07-22 | — | — | EP | disclosed |
| WO-2008040897-A2 | USE IN PERFUMERY AND FLAVOURING AND PROCESS FOR THE PREPARATION OF 5,5-DIMETHYL-3-ETHYL-3,4-DIHYDROFURAN-2-ONE | V. MANE FILS (FR) | 2008-04-10 | — | — | WO | disclosed |