SCHEMBL4144935

SCHEMBL4144935

C=C(C)CC(C(C)=O)C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GRN P28799 1/20 0.36
SORT1 Q99523 1/20 0.36
TET2 Q6N021 3/20 0.36
TET3 O43151 1/20 0.36
TET1 Q8NFU7 1/20 0.36
GRIK1 P39086 2/20 0.34
GRIK2 Q13002 1/20 0.34
GRM1 Q13255 1/20 0.34
GRM2 Q14416 1/20 0.34
TGFBR1 P36897 1/20 0.34
TDP1 Q9NUW8 2/20 0.32
ALDH1A1 P00352 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
SLC7A5 Q01650 1/20 0.31
BHMT Q93088 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9290922 0.89 TET2 (0.39) GRNSORT1TET2TET3TET1
SCHEMBL2294818 0.89 TDP1 (0.35) GRNSORT1TDP1ALDH1A1
SCHEMBL4443797 0.80 TET2 (0.54) TET2TET3TET1GRIK1GRIK2
SCHEMBL4623050 0.78 TDP1 (0.35) GRIK1TDP1ALDH1A1SMN1; SMN2
SCHEMBL8909192 0.78 TDP1 (0.48) TDP1ALDH1A1SMN1; SMN2BHMT
SCHEMBL11309347 0.78 TDP1 (0.48) GRIK1TDP1ALDH1A1SMN1; SMN2
SCHEMBL2045388 0.78 TDP1 (0.48) TDP1ALDH1A1SMN1; SMN2BHMT
SCHEMBL4144659 0.77 ALDH1A1 (0.36) ALDH1A1SMN1; SMN2
SCHEMBL3136053 0.77 MME (0.39) GRNSORT1TET2TET3TET1
SCHEMBL31198158 0.76 TDP1 (0.42) GRNSORT1TET2TET3TET1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119486703-A Fragrance composition with lasting fragrance appearance 弗门尼舍有限公司 2025-02-18 CN claimed
WO-2023247599-A1 FRAGRANCE COMPOSITIONS HAVING LONG-LASTING TRAIL PERFORMANCE FIRMENICH SA (CH) 2023-12-28 WO claimed
EP-0178532-B1 PERFUMING COMPOSITIONS AND PERFUMED ARTICLES CONTAINING ETHYL-2-ACETYL-4-METHYL-4-PENTENOATE FIRMENICH SA (CH) 1990-06-06 EP claimed
EP-0178532-A2 Perfuming compositions and perfumed articles containing ethyl-2-acetyl-4-methyl-4-pentenoate FIRMENICH SA (CH) 1986-04-23 EP claimed
CN-119486703-A Fragrance composition with lasting fragrance appearance 弗门尼舍有限公司 2025-02-18 CN disclosed
US-12024690-B2 Method of countering malodour in a washing machine comprising the addition of a fragrance precursor accord comprising 4-(dodecylthio)-4-methylpentan-2-one GIVAUDAN SA (CH) 2024-07-02 US disclosed
US-12018226-B2 Perfuming compositions FIRMENICH SA (CH) 2024-06-25 US disclosed
EP-4338761-A1 PERFUMING COMPOSITIONS Firmenich SA (CH) 2024-03-20 EP disclosed
WO-2023247599-A1 FRAGRANCE COMPOSITIONS HAVING LONG-LASTING TRAIL PERFORMANCE FIRMENICH SA (CH) 2023-12-28 WO disclosed
US-20220002637-A1 A METHOD OF COUNTERING MALODOUR IN A WASHING MACHINE COMPRISING THE ADDITION OF A FRAGRANCE PRECURSOR GIVAUDAN S.A. (CH) 2022-01-06 US disclosed
EP-3898912-A1 A METHOD OF COUNTERING MALODOUR IN A WASHING MACHINE COMPRISING THE ADDITION OF A FRAGRANCE PRECURSOR Givaudan SA (CH) 2021-10-27 EP disclosed
US-11117860-B2 Phenyl urea derivatives as n-formyl peptide receptor modulators ALLERGAN, INC. (US) 2021-09-14 US disclosed
EP-1951244-A2 CALCILYTIC COMPOUNDS SmithKline Beecham Corporation (US) 2008-08-06 EP disclosed
WO-2007062370-A2 CALCILYTIC COMPOUNDS SMITHKLINE BEECHAM CORPORATION (US) 2007-05-31 WO disclosed
EP-0405427-B1 Aromatic compounds, process for their preparation and their use as perfuming ingredients FIRMENICH & CIE (CH) 1995-03-29 EP disclosed
EP-0178532-B1 PERFUMING COMPOSITIONS AND PERFUMED ARTICLES CONTAINING ETHYL-2-ACETYL-4-METHYL-4-PENTENOATE FIRMENICH SA (CH) 1990-06-06 EP disclosed
EP-0178532-B1 PERFUMING COMPOSITIONS AND PERFUMED ARTICLES CONTAINING ETHYL-2-ACETYL-4-METHYL-4-PENTENOATE FIRMENICH SA (CH) 1990-06-06 EP disclosed
EP-0178532-A2 Perfuming compositions and perfumed articles containing ethyl-2-acetyl-4-methyl-4-pentenoate FIRMENICH SA (CH) 1986-04-23 EP disclosed
EP-0178532-A2 Perfuming compositions and perfumed articles containing ethyl-2-acetyl-4-methyl-4-pentenoate FIRMENICH SA (CH) 1986-04-23 EP disclosed
EP-0178532-A2 Perfuming compositions and perfumed articles containing ethyl-2-acetyl-4-methyl-4-pentenoate FIRMENICH SA (CH) 1986-04-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11117860-B2 Phenyl urea derivatives as n-formyl peptide receptor modulators FPR1, FPR2, FPR3 GRN 817/4885SORT1 2771/4885TET2 4875/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.