⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31058217 | 0.70 | — | — | |
| SCHEMBL189997 | 0.69 | — | — | |
| SCHEMBL13268576 | 0.65 | DAO (0.38) | — | |
| SCHEMBL17048046 | 0.65 | GPR84 (0.42) | — | |
| SCHEMBL21282788 | 0.65 | CHEK1 (0.39) | — | |
| SCHEMBL12284066 | 0.65 | — | — | |
| SCHEMBL4405808 | 0.61 | PDE3B (0.47) | — | |
| SCHEMBL309011 | 0.60 | — | — | |
| SCHEMBL23332221 | 0.58 | IDO1 (0.35) | — | |
| SCHEMBL8188652 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4747249-A1 | TREM2 MODULATORS | Muna Therapeutics ApS (DK) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025017059-A1 | TREM2 MODULATORS | MUNA THERAPEUTICS APS (DK) | 2025-01-23 | — | — | WO | disclosed |