SCHEMBL8188652

SCHEMBL8188652

O=c1cc(Br)[nH]c(=O)[nH]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3995513 0.69
SCHEMBL11844328 0.67 GPR84 (0.50)
SCHEMBL18836780 0.67 GPR84 (0.52)
SCHEMBL60308 0.67
SCHEMBL189997 0.67
SCHEMBL13918178 0.67
SCHEMBL3362001 0.67
SCHEMBL325682 0.67
SCHEMBL1896344 0.67
SCHEMBL1774205 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102676595-A Method for producing reduced coenzyme Q10 by fermentation of recombinant strains SUZHOU HYGIA BIOLOG TECHNOLOGY CO LTD 2012-09-19 CN claimed
CN-102676595-A Method for producing reduced coenzyme Q10 by fermentation of recombinant strains SUZHOU HYGIA BIOLOG TECHNOLOGY CO LTD 2012-09-19 CN disclosed
US-6017923-A Carbo-acyclic nucleoside derivatives as antiviral and antineoplastic agents HOECHST MARION ROUSSEL, INC. (US) 2000-01-25 US disclosed
EP-0705264-B1 CARBO-ACYCLIC NUCLEOSIDE DERIVATIVES AS ANTIVIRAL AND ANTINEOPLASTIC AGENTS MERRELL PHARMA INC (US) 1999-04-07 EP disclosed
CN-1204648-A Carbo-acyclic nucleoside derivatives as antiviral and antineoplastic agents MERRELL PHARMA INC (US) 1999-01-13 CN disclosed
CN-1040759-C Carbo-acyclic nucleoside derivatives as antiviral and antitumor agents MERRELL DOW PHARMA (US) 1998-11-18 CN disclosed
CN-1125947-A Carbo-acyclic nucleoside derivatives as antiviral and antitumor agents MERRELL DOW PHARMA (US) 1996-07-03 CN disclosed
EP-0705264-A1 CARBO-ACYCLIC NUCLEOSIDE DERIVATIVES AS ANTIVIRAL AND ANTINEOPLASTIC AGENTS MERRELL PHARMACEUTICALS INC. (US) 1996-04-10 EP disclosed
WO-1995000515-A1 CARBO-ACYCLIC NUCLEOSIDE DERIVATIVES AS ANTIVIRAL AND ANTINEOPLASTIC AGENTS MERRELL PHARMACEUTICALS INC. (US) 1995-01-05 WO disclosed