Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 1/20 | 0.51 |
| ▸ | VNN1 | O95497 | 3/20 | 0.48 |
| ▸ | AURKA | O14965 | 2/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ASPH | Q12797 | 2/20 | 0.46 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.46 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.45 |
| ▸ | CDK2 | P24941 | 2/20 | 0.45 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.45 |
| ▸ | NCF1 | P14598 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23039888 | 1.00 | CD38 (0.51) | CD38VNN1AURKARPS6KB1KDM4E | |
| SCHEMBL31361060 | 0.78 | CD38 (0.52) | CD38VNN1AURKARPS6KB1KDM4E | |
| SCHEMBL2481240 | 0.77 | KDM4E (0.56) | CD38VNN1AURKARPS6KB1KDM4E | |
| SCHEMBL29499805 | 0.74 | TSHR (0.55) | KDM4ENCF1ALDH1A1GAAMEN1 | |
| SCHEMBL23040086 | 0.74 | TSHR (0.55) | KDM4ENCF1ALDH1A1GAAMEN1 | |
| SCHEMBL23055296 | 0.74 | ALDH1A1 (0.36) | KDM4EL3MBTL1ALDH1A1GAAMEN1 | |
| SCHEMBL6103515 | 0.73 | KDM4E (0.53) | VNN1AURKARPS6KB1KDM4EASPH | |
| SCHEMBL30590416 | 0.73 | VNN1 (0.46) | VNN1AURKARPS6KB1KDM4EASPH | |
| SCHEMBL31139804 | 0.73 | KDM4E (0.53) | VNN1AURKARPS6KB1KDM4EASPH | |
| SCHEMBL14957558 | 0.73 | TUBB4A (0.55) | VNN1AURKARPS6KB1KDM4EASPH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114302884-B | Substituted pyridopyrimidinone compounds useful as T cell activators | 百时美施贵宝公司 | 2024-06-04 | — | — | CN | disclosed |
| EP-4021901-A1 | SUBSTITUTED PYRIDOPYRIMIDINONYL COMPOUNDS USEFUL AS T CELL ACTIVATORS | Bristol-Myers Squibb Company (US) | 2022-07-06 | — | — | EP | disclosed |
| CN-114302884-A | Substituted pyridopyrimidinone based compounds useful as T cell activators | 百时美施贵宝公司 | 2022-04-08 | — | — | CN | disclosed |