Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.39 |
| ▸ | MAT2A | P31153 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.35 |
| ▸ | HTR1A | P08908 | 3/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | TACR3 | P29371 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31361364 | 0.93 | KMT2A (0.40) | NPSR1MEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL31361455 | 0.92 | KMT2A (0.40) | NPSR1MEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL31361311 | 0.91 | HTT (0.39) | NPSR1MEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL31361399 | 0.91 | RNASEH1 (0.40) | NPSR1MEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL31361426 | 0.91 | MAT2A (0.41) | NPSR1MEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL31361381 | 0.90 | KMT2A (0.38) | NPSR1MEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL31361366 | 0.90 | KMT2A (0.38) | NPSR1MEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL31361336 | 0.90 | KMT2A (0.38) | NPSR1MEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL31361356 | 0.89 | KMT2A (0.41) | NPSR1MEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL31361393 | 0.89 | KMT2A (0.37) | NPSR1MEN1KMT2AHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999232-B | MAT2A inhibitors | 南京正大天晴制药有限公司 | 2025-01-07 | — | — | CN | disclosed |