Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAT2A | P31153 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | GALR2 | O43603 | 1/20 | 0.36 |
| ▸ | GALR1 | P47211 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31361364 | 0.93 | KMT2A (0.40) | HTTMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL31361455 | 0.92 | KMT2A (0.40) | HTTMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL31361380 | 0.91 | NPSR1 (0.43) | HTTMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL31361426 | 0.90 | MAT2A (0.41) | HTTMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL31361399 | 0.90 | RNASEH1 (0.40) | HTTMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL31361381 | 0.89 | KMT2A (0.38) | HTTMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL31361336 | 0.89 | KMT2A (0.38) | HTTMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL31361366 | 0.89 | KMT2A (0.38) | HTTMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL31361393 | 0.88 | KMT2A (0.37) | HTTMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL31361416 | 0.87 | TUBB4A (0.41) | HTTMEN1KMT2ANPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999232-B | MAT2A inhibitors | 南京正大天晴制药有限公司 | 2025-01-07 | — | — | CN | disclosed |