Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | USP1 | O94782 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31361627 | 0.88 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNAPOLBKMT2A | |
| SCHEMBL30990360 | 0.80 | ALDH1A1 (0.52) | ALDH1A1MAPTLMNAPOLBKMT2A | |
| SCHEMBL25239760 | 0.79 | ALDH1A1 (0.48) | ALDH1A1MAPTLMNAGAACYP2C9 | |
| SCHEMBL17278808 | 0.78 | ALDH1A1 (0.53) | ALDH1A1MAPTLMNAPOLBKMT2A | |
| SCHEMBL16012381 | 0.77 | ALDH1A1 (0.52) | ALDH1A1MAPTLMNAKMT2AHTT | |
| SCHEMBL27940259 | 0.77 | CYP11B2 (0.39) | USP1NAMPTJAK2JAK1 | |
| SCHEMBL16985535 | 0.76 | ALDH1A1 (0.43) | ALDH1A1MAPTLMNAKCNH2 | |
| SCHEMBL31306767 | 0.75 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNANAMPTKCNH2 | |
| SCHEMBL31639840 | 0.74 | MAPT (0.48) | ALDH1A1MAPTLMNAKMT2AMEN1 | |
| SCHEMBL16652728 | 0.73 | MAPT (0.42) | ALDH1A1MAPTLMNAPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025017116-A1 | PHARMACEUTICAL COMPOUNDS HAVING ACTIVITY AS WEE1 INHIBITORS | SENTINEL ONCOLOGY LIMITED (GB) | 2025-01-23 | — | — | WO | disclosed |