Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16975393 | 0.82 | IRAK4 (0.40) | KDM5AALOX15GAASMN1; SMN2 | |
| SCHEMBL31361720 | 0.79 | KDM5A (0.36) | KDM5AJAK2JAK1TYK2JAK3 | |
| SCHEMBL9953033 | 0.78 | KDM5A (0.47) | KDM5AALOX15GAASMN1; SMN2 | |
| SCHEMBL23685815 | 0.78 | KDM5A (0.47) | KDM5AALOX15GAASMN1; SMN2 | |
| SCHEMBL31361718 | 0.78 | KDM5A (0.47) | KDM5AALOX15GAASMN1; SMN2 | |
| SCHEMBL15650297 | 0.78 | JAK2 (0.41) | KDM5AJAK2JAK1TYK2JAK3 | |
| SCHEMBL31361694 | 0.77 | ALDH1A1 (0.39) | GAA | |
| SCHEMBL216558 | 0.74 | ALOX15 (0.50) | KDM5AALOX15GAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL15145595 | 0.73 | ALOX15 (0.49) | KDM5AALOX15GAASMN1; SMN2 | |
| SCHEMBL17076683 | 0.73 | KDM5A (0.43) | KDM5AALOX15GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025017116-A1 | PHARMACEUTICAL COMPOUNDS HAVING ACTIVITY AS WEE1 INHIBITORS | SENTINEL ONCOLOGY LIMITED (GB) | 2025-01-23 | — | — | WO | disclosed |