Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | PLAU | P00749 | 2/20 | 0.34 |
| ▸ | ELANE | P08246 | 2/20 | 0.34 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16985296 | 0.85 | IRAK4 (0.41) | ALDH1A1L3MBTL1CYP2D6HTTF2 | |
| SCHEMBL31361731 | 0.82 | L3MBTL1 (0.41) | ALDH1A1L3MBTL1F2PLAUELANE | |
| SCHEMBL31361661 | 0.81 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1CYP2D6HTTF2 | |
| SCHEMBL9952208 | 0.81 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1CYP2D6HTTF2 | |
| SCHEMBL16985417 | 0.81 | SLC18A3 (0.44) | ALDH1A1L3MBTL1F2PLAUELANE | |
| SCHEMBL16985405 | 0.79 | ALDH1A1 (0.44) | ALDH1A1MAPTLMNAHPGD | |
| SCHEMBL1558099 | 0.78 | SIRT6 (0.40) | ALDH1A1L3MBTL1ACHEMAPTLMNA | |
| SCHEMBL31361722 | 0.77 | KDM5A (0.37) | GAA | |
| SCHEMBL17027309 | 0.76 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1KMT2AMAPTLMNA | |
| SCHEMBL31361604 | 0.75 | JAK2 (0.38) | ALDH1A1L3MBTL1F2PLAUELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025017116-A1 | PHARMACEUTICAL COMPOUNDS HAVING ACTIVITY AS WEE1 INHIBITORS | SENTINEL ONCOLOGY LIMITED (GB) | 2025-01-23 | — | — | WO | disclosed |