SCHEMBL29397746

SCHEMBL29397746

CC(C)C[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](C)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O)[C@@H](C)O)C(C)C

nearest known ligand 0.73

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ NPY2R P49146 8/20 0.73
▸ NPY4R P50391 8/20 0.73
▸ NPY5R Q15761 8/20 0.73
▸ NPY1R P25929 6/20 0.73
▸ TFPI P10646 5/20 0.67
▸ CALCR P30988 5/20 0.67
▸ RAMP3 O60896 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29496391 0.97 NPY2R (0.72) NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL13248707 0.96 NPY2R (0.80) NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL29496288 0.95 NPY2R (0.74) NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL29783624 0.93 CALCR (0.73) NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL29783636 0.93 CALCR (0.73) NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL29783640 0.93 CALCR (0.73) NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL29783629 0.93 CALCR (0.73) NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL29783631 0.93 CALCR (0.73) NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL29783626 0.93 CALCR (0.73) NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL29526997 0.93 NPY2R (0.72) NPY2RNPY4RNPY5RNPY1RTFPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 228 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112888705-B Protein tyrosine-tyrosine analogues and methods of use thereof 伊莱利利公司 2025-03-11 — — CN claimed
CN-119156221-A Improved oral pharmaceutical formulations of therapeutic peptides and proteins 西普鲁梅有限公司 2024-12-17 — — CN claimed
WO-2024212843-A1 PEPTIDE TYROSINE-TYROSINE ANALOG AND USE THEREOF 联邦生物科技(珠海横琴)有限公司 2024-10-17 — — WO claimed
CN-114075265-A Polypeptide tyrosine analogue and sustained-release preparation containing same 丽珠医药集团股份有限公司 2022-02-22 — — CN claimed
CN-122097550-A GLP-1 and PYY3-36Polypeptide analogue composition and preparation method and application thereof — 2026-05-29 — — CN disclosed
EP-4743083-A1 METHODS OF TREATING FIBROTIC LIVER DISEASES OR CONDITIONS WITH INDEGLITAZAR Pleiogenix Inc. (US) 2026-05-20 — — EP disclosed
EP-4199925-B1 CYCLOPENTAPYRROLE OREXIN RECEPTOR AGONISTS MERCK SHARP & DOHME LLC (US) 2026-05-20 — — EP disclosed
EP-3257523-B1 USE OF POLYPEPTIDE COMPLEX AS POLYPEPTIDE OR PROTEIN DRUG CARRIER, METHOD, AND FUSION PROTEIN COMPLEX THEREOF TIANJIN INST IND BIOTECHNOLOGY CAS (CN) 2026-05-20 — — EP disclosed
US-12624002-B2 Dimers for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-05-12 — — US disclosed
US-12617830-B2 Analogues of PYY IP2IPO INNOVATIONS LIMITED (GB) 2026-05-05 — — US disclosed
CN-121895435-A PYY analogue and application thereof in treatment of diseases 孙涛 2026-04-21 — — CN disclosed
US-12600699-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-14 — — US disclosed
CN-107001485-B Protein heterodimers and uses thereof 苏州丁孚靶点生物技术有限公司 2022-03-22 — — CN disclosed
EP-3966201-A1 THIOSEMICARBAZATES AND USES THEREOF The Feinstein Institutes for Medical Research (US) 2022-03-16 — — EP disclosed
EP-3966223-A1 PEPTIDOMIMETIC AGENTS, SYNTHESIS AND USES THEREOF The Feinstein Institutes for Medical Research (US) 2022-03-16 — — EP disclosed
CN-114126619-A Compounds for the synthesis of peptidomimetics 范因斯坦医学研究院 2022-03-01 — — CN disclosed
WO-2022040058-A1 CYCLOPENTAPYRROLE OREXIN RECEPTOR AGONISTS MERCK SHARP & DOHME CORP. (US) 2022-02-24 — — WO disclosed
WO-2022040070-A1 BICYCLOHEPTANE PYRROLIDINE OREXIN RECEPTOR AGONISTS MERCK SHARP & DOHME CORP. (US) 2022-02-24 — — WO disclosed
US-20220056017-A1 BICYCLOHEPTANE PYRROLIDINE OREXIN RECEPTOR AGONISTS MERCK SHARP & DOHME CORP. (US) 2022-02-24 — — US disclosed
CN-114075265-A Polypeptide tyrosine analogue and sustained-release preparation containing same 丽珠医药集团股份有限公司 2022-02-22 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12624002-B2 Dimers for use in synthesis of peptidomimetics GLUL, ARGLU1, ASNS NPY2R 111/4885NPY4R 74/4885NPY5R 247/4885
US-12617830-B2 Analogues of PYY GLP1R, INSR, GIPR NPY2R 31/4885NPY4R 22/4885NPY5R 81/4885
US-20220056017-A1 BICYCLOHEPTANE PYRROLIDINE OREXIN RECEPTOR AGONISTS HCRTR1, HCRTR2, CRHR1 NPY2R 7/4885NPY4R 14/4885NPY5R 12/4885
US-12600699-B2 Thiosemicarbazates and uses thereof MET, THRB, ABAT NPY2R 791/4885NPY4R 331/4885NPY5R 500/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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