Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26026951 | 0.82 | GRM5 (0.36) | GRM5ALDH1A1MAP4K4NR1H2MEN1 | |
| SCHEMBL22279667 | 0.82 | MAP4K4 (0.39) | GRM5ALDH1A1MAP4K4NR1H2MEN1 | |
| SCHEMBL30519529 | 0.80 | GPR119 (0.42) | GRM5NR1H2NR1H3 | |
| SCHEMBL26027032 | 0.80 | GPR119 (0.42) | GRM5NR1H2NR1H3 | |
| SCHEMBL30622756 | 0.76 | GRM5 (0.45) | GRM5ALDH1A1NR1H2MEN1KMT2A | |
| SCHEMBL31692206 | 0.76 | UCHL1 (0.38) | ALDH1A1L3MBTL1LMNAKMT2ANPSR1 | |
| SCHEMBL24276770 | 0.75 | GRM5 (0.36) | GRM5ALDH1A1NR1H2LMNANPSR1 | |
| SCHEMBL34469131 | 0.74 | MAP4K4 (0.38) | GRM5ALDH1A1MAP4K4 | |
| SCHEMBL31155235 | 0.74 | MAP4K4 (0.38) | GRM5ALDH1A1MAP4K4 | |
| SCHEMBL30623037 | 0.74 | NR1H2 (0.43) | GRM5NR1H2MAPTNR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025034858-A1 | FUSED PYRIDINES FOR THE TREATMENT OF CANCER AND OTHER INDICATIONS | THERAS, INC. (US) | 2025-02-13 | — | — | WO | disclosed |