Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.40 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 4/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | INSR | P06213 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | WEE1 | P30291 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31362368 | 0.91 | DRD2 (0.44) | DRD2CDK4CDK2CDK6ABHD6 | |
| SCHEMBL31362508 | 0.84 | DRD2 (0.44) | DRD2CDK4CDK2CDK6ALK | |
| SCHEMBL27975062 | 0.82 | MAPT (0.38) | ABHD6ADORA2AMAPT | |
| SCHEMBL1640454 | 0.78 | HSP90AB1 (0.40) | ABHD6ADORA2AMAPT | |
| SCHEMBL31362571 | 0.75 | DRD2 (0.46) | DRD2CDK4CDK2CDK6ALK | |
| SCHEMBL15309449 | 0.74 | ABHD6 (0.49) | ABHD6 | |
| SCHEMBL723952 | 0.72 | ABHD6 (0.49) | ABHD6GRM5 | |
| SCHEMBL17141806 | 0.72 | MAPK1 (0.40) | — | |
| SCHEMBL8022098 | 0.71 | CYP2C19 (0.44) | ABHD6ADORA2AMAPTKMT2A | |
| SCHEMBL30033295 | 0.71 | CYP2C19 (0.44) | ABHD6ADORA2AMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025034858-A1 | FUSED PYRIDINES FOR THE TREATMENT OF CANCER AND OTHER INDICATIONS | THERAS, INC. (US) | 2025-02-13 | — | — | WO | disclosed |