Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 4/20 | 0.36 |
| ▸ | WEE1 | P30291 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 5/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 4/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.35 |
| ▸ | INSR | P06213 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31362571 | 0.91 | DRD2 (0.46) | DRD2CDK4CDK2CDK6HTR6 | |
| SCHEMBL31362450 | 0.84 | DRD2 (0.42) | DRD2CDK4CDK2CDK6HTR6 | |
| SCHEMBL31362283 | 0.78 | PDCD1 (0.38) | DRD2 | |
| SCHEMBL24752579 | 0.76 | CYP2C19 (0.44) | MEN1KMT2AHSP90AA1 | |
| SCHEMBL30032785 | 0.76 | CYP2C19 (0.44) | MEN1KMT2AHSP90AA1 | |
| SCHEMBL31362368 | 0.75 | DRD2 (0.44) | DRD2CDK4CDK2CDK6HTR6 | |
| SCHEMBL25429414 | 0.71 | MAPK1 (0.49) | CDK4CDK2CDK6CDK9MEN1 | |
| SCHEMBL30519665 | 0.71 | MAPT (0.52) | — | |
| SCHEMBL2559734 | 0.71 | MAPT (0.52) | — | |
| SCHEMBL20910192 | 0.69 | MEN1 (0.49) | DRD2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025034858-A1 | FUSED PYRIDINES FOR THE TREATMENT OF CANCER AND OTHER INDICATIONS | THERAS, INC. (US) | 2025-02-13 | — | — | WO | disclosed |