Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 10/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | STK17B | O94768 | 1/20 | 0.38 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2946716 | 0.82 | AAK1 (0.46) | AAK1HTTNPSR1NQO2STK17B | |
| SCHEMBL16552184 | 0.82 | STK17B (0.47) | AAK1HTTNPSR1NQO2STK17B | |
| SCHEMBL31362427 | 0.81 | AAK1 (0.40) | AAK1HTTNPSR1NQO2STK17B | |
| SCHEMBL31569504 | 0.76 | TDP1 (0.41) | AAK1HTTNPSR1NQO2STK17B | |
| SCHEMBL23854682 | 0.74 | MTNR1B (0.45) | AAK1HTTNPSR1NQO2STK17B | |
| SCHEMBL21594070 | 0.74 | MTNR1B (0.42) | AAK1HTTNPSR1NQO2STK17B | |
| SCHEMBL13607699 | 0.73 | CPB2 (0.44) | HTTNPSR1NQO2STK17BSTK17A | |
| SCHEMBL16814130 | 0.73 | AAK1 (0.51) | AAK1STK17BSTK17A | |
| SCHEMBL29918736 | 0.73 | AAK1 (0.51) | AAK1STK17BSTK17A | |
| SCHEMBL15367044 | 0.73 | CYP3A4 (0.44) | HTTNPSR1NQO2STK17BSTK17A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025034858-A1 | FUSED PYRIDINES FOR THE TREATMENT OF CANCER AND OTHER INDICATIONS | THERAS, INC. (US) | 2025-02-13 | — | — | WO | disclosed |