Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 7/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 3/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21769766 | 0.81 | OPRK1 (0.44) | OPRK1TSHRHTTALDH1A1KDM4E | |
| SCHEMBL21591650 | 0.79 | PTGDR2 (0.40) | OPRK1PTGDR2TSHRHTTMAOA | |
| SCHEMBL29337246 | 0.72 | OPRK1 (0.43) | OPRK1PTGDR2TSHRHTTMAOA | |
| SCHEMBL3369691 | 0.71 | CYP11B1 (0.34) | HTT | |
| SCHEMBL14920257 | 0.71 | PLAU (0.39) | HTTALDH1A1KDM4E | |
| SCHEMBL4172345 | 0.71 | ALDH1A1 (0.35) | HTTALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL18068209 | 0.71 | SMN1; SMN2 (0.52) | OPRK1PTGDR2TSHRHTTMAOA | |
| SCHEMBL9648890 | 0.69 | OPRK1 (0.42) | OPRK1PTGDR2TSHRHTTMAOA | |
| SCHEMBL1600624 | 0.69 | OPRK1 (0.42) | OPRK1PTGDR2TSHRHTTMAOA | |
| SCHEMBL11992010 | 0.69 | HTT (0.50) | OPRK1PTGDR2TSHRHTTMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025034858-A1 | FUSED PYRIDINES FOR THE TREATMENT OF CANCER AND OTHER INDICATIONS | THERAS, INC. (US) | 2025-02-13 | — | — | WO | disclosed |