Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11784286 | 0.84 | CA2 (0.34) | KMT2AMAPTCA2HDAC3HDAC4 | |
| SCHEMBL2967568 | 0.83 | CA1 (0.40) | KMT2AMAPTCA1CA2CA5A | |
| SCHEMBL1828511 | 0.83 | PDK1 (0.41) | KMT2AMAPTCA1CA2CA5A | |
| SCHEMBL7768184 | 0.82 | KMT2A (0.53) | KMT2AMAPTCA1CA2CA5A | |
| SCHEMBL5322102 | 0.81 | PRNP (0.37) | KMT2AMAPTCA1CA2CA9 | |
| SCHEMBL31189227 | 0.81 | PRNP (0.37) | KMT2AMAPTCA1CA2CA9 | |
| SCHEMBL31619483 | 0.80 | CA1 (0.46) | KMT2AMAPTCA1CA2CA5A | |
| SCHEMBL22636306 | 0.80 | CYP1A2 (0.43) | KMT2AMAPTCA1CA2CA5A | |
| SCHEMBL548019 | 0.79 | PLCG1 (0.49) | KMT2AMAPTCA1CA2CA5A | |
| SCHEMBL5199900 | 0.77 | CYP2C9 (0.50) | KMT2AMAPTCA1CA2CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2532644-A1 | Preparation of 2-(4-bromophenyl)-2-methylpropanoic acid | Divi's Laboratories Limited (IN) | 2012-12-12 | — | — | EP | disclosed |
| EP-2532644-A1 | Preparation of 2-(4-bromophenyl)-2-methylpropanoic acid | Divi's Laboratories Limited (IN) | 2012-12-12 | — | — | EP | disclosed |
| US-20120309973-A1 | PREPARATION OF 2-(4-BROMOPHENYL)-2-METHYLPROPANOIC ACID | DIVI'S LABORATORIES LIMITED (IN) | 2012-12-06 | — | — | US | disclosed |
| US-20120309973-A1 | PREPARATION OF 2-(4-BROMOPHENYL)-2-METHYLPROPANOIC ACID | DIVI'S LABORATORIES LIMITED (IN) | 2012-12-06 | — | — | US | disclosed |
| US-20120309973-A1 | PREPARATION OF 2-(4-BROMOPHENYL)-2-METHYLPROPANOIC ACID | DIVI'S LABORATORIES LIMITED (IN) | 2012-12-06 | — | — | US | disclosed |
| WO-2010007253-A2 | NOVEL METHOD FOR PREPARING FUNCTIONALIZED BENZOCYCLOBUTENES, AND USE IN THE SYNTHESIS OF IVABRADINE AND OF ADDITION SALTS THEREOF WITH A PHARMACEUTICALLY ACCEPTABLE ACID | LES LABORATOIRES SERVIER (FR) | 2010-01-21 | — | — | WO | disclosed |
| EP-2145871-A1 | New method for preparing functionalised benzocyclobutenes and its application to the synthesis of ivabradine and its addition salts with a pharmaceutically acceptable acid. | Les Laboratoires Servier (FR) | 2010-01-20 | — | — | EP | disclosed |
| CN-87103809-A | The method for making of naphthane and indan derivative | — | 1987-12-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120309973-A1 | PREPARATION OF 2-(4-BROMOPHENYL)-2-METHYLPROPANOIC ACID | HRH2, NPFFR2, GABRA6 | KMT2A 141/4885MAPT 1798/4885CA1 1754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.