Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 2/20 | 0.38 |
| ▸ | CASP7 | P55210 | 2/20 | 0.38 |
| ▸ | CASP6 | P55212 | 2/20 | 0.38 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.38 |
| ▸ | CASP2 | P42575 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | FER | P16591 | 1/20 | 0.37 |
| ▸ | LTK | P29376 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30215653 | 0.78 | IDO1 (0.46) | GSK3BPARP1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL11642970 | 0.76 | GSK3B (0.37) | GSK3BCASP3CASP7CASP6CASP8 | |
| SCHEMBL28979780 | 0.76 | GSK3B (0.48) | GSK3BCASP3CASP7CASP6CASP8 | |
| SCHEMBL28358252 | 0.74 | GPR3 (0.41) | HTR2A | |
| SCHEMBL28979779 | 0.73 | CES1 (0.47) | GSK3BHTR2AHTR2CHTR2BPARP1 | |
| SCHEMBL11844924 | 0.73 | GSK3B (0.50) | GSK3BCASP3CASP7CASP6CASP8 | |
| SCHEMBL2337529 | 0.72 | GSK3B (0.48) | GSK3BCASP3CASP7CASP6CASP8 | |
| SCHEMBL5551044 | 0.72 | GSK3B (0.48) | GSK3BCASP3CASP7CASP6CASP8 | |
| SCHEMBL30556308 | 0.71 | MAOA (0.41) | GSK3BPDGFRAFERLTKCDK8 | |
| SCHEMBL29920200 | 0.70 | TNKS2 (0.45) | GSK3BTNKS2HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115747843-B | Electrochemical preparation method for synthesizing fluoroisoquinoline-1, 3-diketone compound by trifluoromethyl/cyclization | 兰州石化职业技术大学 | 2025-01-24 | — | — | CN | disclosed |
| CN-115747843-B | Electrochemical preparation method for synthesizing fluoroisoquinoline-1, 3-diketone compound by trifluoromethyl/cyclization | 兰州石化职业技术大学 | 2025-01-24 | — | — | CN | disclosed |