SCHEMBL31362908

SCHEMBL31362908

O=C1C(Cl)=C(Cl)C(=O)c2ncccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100A4 P26447 6/20 1.00
CDC25B P30305 3/20 1.00
NSD2 O96028 5/20 0.65
TDP2 O95551 3/20 0.65
PAX8 Q06710 3/20 0.65
ABL1 P00519 1/20 0.65
PLCG1 P19174 1/20 0.65
CES1 P23141 1/20 0.65
RIN1 Q13671 1/20 0.65
MEN1 O00255 1/20 0.65
THRB P10828 1/20 0.65
BLM P54132 1/20 0.65
KMT2A Q03164 1/20 0.65
TDP1 Q9NUW8 1/20 0.65
GAA P10253 1/20 0.65
PTPRC P08575 2/20 0.59
CTSL P07711 1/20 0.59
CTSS P25774 1/20 0.59
PTPN13 Q12923 1/20 0.59
IDO1 P14902 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1612462 1.00 S100A4 (1.00) S100A4CDC25BNSD2TDP2PAX8
SCHEMBL16745449 0.87 S100A4 (0.77) S100A4CDC25BNSD2TDP2PAX8
SCHEMBL1612515 0.85 S100A4 (1.00) S100A4CDC25BNSD2TDP2PAX8
SCHEMBL6294370 0.85 S100A4 (0.87) S100A4CDC25BNSD2TDP2PAX8
SCHEMBL5915065 0.84 TDP2 (0.81) S100A4CDC25BNSD2TDP2PAX8
SCHEMBL7692908 0.84 CDC25B (0.71) S100A4CDC25BNSD2TDP2PAX8
SCHEMBL5915061 0.82 GAA (0.86) S100A4CDC25BNSD2TDP2PAX8
SCHEMBL7690116 0.82 S100A4 (0.69) S100A4CDC25BNSD2TDP2PAX8
SCHEMBL9669361 0.82 S100A4 (0.69) S100A4CDC25BNSD2TDP2PAX8
SCHEMBL17918976 0.81 S100A4 (0.69) S100A4CDC25BNSD2TDP2PAX8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119636435-A Locomotive converter system and method integrating main and auxiliary supply functions 国能朔黄铁路发展有限责任公司 2025-03-18 CN disclosed