SCHEMBL7690116

SCHEMBL7690116

COC1=C(Cl)C(=O)c2cccnc2C1=O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100A4 P26447 6/20 0.69
CDC25B P30305 3/20 0.69
HKDC1 Q2TB90 2/20 0.62
PADI1 Q9ULC6 2/20 0.62
PADI3 Q9ULW8 2/20 0.62
PADI4 Q9UM07 2/20 0.62
PADI2 Q9Y2J8 2/20 0.62
ATG4B Q9Y4P1 1/20 0.62
NSD2 O96028 4/20 0.53
TDP2 O95551 2/20 0.53
PAX8 Q06710 2/20 0.53
ABL1 P00519 1/20 0.53
PLCG1 P19174 1/20 0.53
CES1 P23141 1/20 0.53
RIN1 Q13671 1/20 0.53
MEN1 O00255 1/20 0.53
THRB P10828 1/20 0.53
BLM P54132 1/20 0.53
KMT2A Q03164 1/20 0.53
TDP1 Q9NUW8 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9669361 0.93 S100A4 (0.69) S100A4CDC25BHKDC1PADI1PADI3
SCHEMBL7689806 0.86 S100A4 (0.75) S100A4CDC25BHKDC1PADI1PADI3
SCHEMBL1612462 0.82 S100A4 (1.00) S100A4CDC25BHKDC1PADI1PADI3
SCHEMBL31362908 0.82 S100A4 (1.00) S100A4CDC25BHKDC1PADI1PADI3
SCHEMBL6300142 0.79 S100A4 (0.71) S100A4CDC25BHKDC1PADI1PADI3
SCHEMBL2599160 0.77 S100A4 (1.00) S100A4CDC25BHKDC1PADI1PADI3
SCHEMBL8285443 0.76 MAPT (0.71) CDC25BHKDC1NSD2MEN1THRB
SCHEMBL6294370 0.76 S100A4 (0.87) S100A4CDC25BHKDC1PADI1PADI3
SCHEMBL5915065 0.75 TDP2 (0.81) S100A4CDC25BHKDC1PADI1PADI3
SCHEMBL30754598 0.75 S100A4 (0.56) S100A4CDC25BHKDC1PADI1PADI3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002034742-A1 AZIRIDINYLQUINOLINEDIONE DERIVATIVES AND PROCESS FOR THEIR PREPARATION KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2002-05-02 WO disclosed