Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.33 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.32 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.30 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20927651 | 0.84 | F2 (0.34) | GPR119KCNQ4KCNQ5ALDH1A1F2 | |
| SCHEMBL23144395 | 0.84 | HRH4 (0.38) | GPR119KCNQ4KCNQ5 | |
| SCHEMBL29812119 | 0.84 | HRH4 (0.38) | GPR119KCNQ4KCNQ5 | |
| SCHEMBL23144580 | 0.84 | PDK1 (0.37) | GPR119PDK1PDK2PDK3PDK4 | |
| SCHEMBL29811656 | 0.84 | PDK1 (0.37) | GPR119PDK1PDK2PDK3PDK4 | |
| SCHEMBL23144640 | 0.83 | SMN1; SMN2 (0.40) | GPR119SMN1; SMN2 | |
| SCHEMBL29811519 | 0.83 | SMN1; SMN2 (0.40) | GPR119SMN1; SMN2 | |
| SCHEMBL23155582 | 0.82 | HRH4 (0.36) | GPR119 | |
| SCHEMBL29811716 | 0.82 | HRH4 (0.36) | GPR119 | |
| SCHEMBL31363594 | 0.82 | GPR119 (0.37) | GPR119SMN1; SMN2CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059074-A1 | BICYCLIC COMPOUNDS FOR RESTORING MUTANT P53 FUNCTION | PMV PHARMACEUTICALS, INC. (US) | 2025-03-20 | — | — | WO | disclosed |