Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31363420 | 0.83 | PDE4A (0.31) | PDE4AMAPT | |
| SCHEMBL30520974 | 0.74 | PDE4A (0.52) | PDE4AALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL31258497 | 0.74 | CA12 (0.46) | PDE4AALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL31258494 | 0.74 | CA12 (0.46) | PDE4AALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL29786151 | 0.72 | PDE4A (0.53) | PDE4AALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL31363285 | 0.72 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2MAPTIDO1NPC1 | |
| SCHEMBL8977944 | 0.71 | PDE4A (0.43) | PDE4AALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL14656701 | 0.71 | EGLN1 (0.53) | PDE4AALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL22577794 | 0.71 | ALDH1A1 (0.42) | PDE4AALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL17781174 | 0.71 | PDE4A (0.48) | PDE4AALDH1A1MAPTIDO1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059074-A1 | BICYCLIC COMPOUNDS FOR RESTORING MUTANT P53 FUNCTION | PMV PHARMACEUTICALS, INC. (US) | 2025-03-20 | — | — | WO | disclosed |