Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31363537 | 0.86 | MAPT (0.38) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL22438504 | 0.72 | KDM4E (0.50) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL31364057 | 0.72 | PDE4A (0.41) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL20920785 | 0.68 | PDE3B (0.47) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL3908929 | 0.68 | MAPT (0.40) | ALDH1A1CYP1A2CYP2C19NPC1RAB9A | |
| SCHEMBL26146309 | 0.66 | ALDH1A1 (0.46) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL23115813 | 0.66 | SMN1; SMN2 (0.45) | ALDH1A1CYP1A2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14799952 | 0.65 | RAB9A (0.49) | ALDH1A1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL20923359 | 0.65 | FNTA (0.46) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL15300028 | 0.65 | LMNA (0.48) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059074-A1 | BICYCLIC COMPOUNDS FOR RESTORING MUTANT P53 FUNCTION | PMV PHARMACEUTICALS, INC. (US) | 2025-03-20 | — | — | WO | disclosed |