Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 7/20 | 0.61 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.42 |
| ▸ | DUT | P33316 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.35 |
| ▸ | CHRNG | P07510 | 2/20 | 0.35 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.35 |
| ▸ | CHRND | Q07001 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27341000 | 0.84 | KIF11 (0.77) | KIF11KCNN4DUTKCNH2 | |
| SCHEMBL7263720 | 0.83 | KIF11 (0.65) | KIF11KCNN4DUTMIFALDH1A1 | |
| SCHEMBL7268298 | 0.83 | KIF11 (0.65) | KIF11KCNN4DUTMIFALDH1A1 | |
| SCHEMBL2283152 | 0.83 | KIF11 (0.74) | KIF11KCNN4DUT | |
| SCHEMBL7268289 | 0.81 | KIF11 (0.67) | KIF11KCNN4DUTMIFALDH1A1 | |
| SCHEMBL15160759 | 0.81 | KIF11 (0.71) | KIF11KCNN4DUT | |
| SCHEMBL7262278 | 0.79 | KIF11 (0.59) | KIF11KCNN4DUTMIFALDH1A1 | |
| SCHEMBL7269694 | 0.79 | KIF11 (0.59) | KIF11KCNN4DUTMIFALDH1A1 | |
| SCHEMBL1105545 | 0.77 | KIF11 (1.00) | KIF11KCNN4DUT | |
| SCHEMBL12264133 | 0.76 | KIF11 (0.68) | KIF11KCNN4DUTALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230144106-A1 | COMPOUNDS FOR THE MODULATION OF MYC ACTIVITY | SYROS PHARMACEUTICALS INC (US) | 2023-05-11 | — | — | US | disclosed |
| US-20230144106-A1 | COMPOUNDS FOR THE MODULATION OF MYC ACTIVITY | SYROS PHARMACEUTICALS INC (US) | 2023-05-11 | — | — | US | disclosed |
| US-20210188833-A1 | COMPOUNDS FOR THE MODULATION OF MYC ACTIVITY | SYROS PHARMACEUTICALS INC (US) | 2021-06-24 | — | — | US | disclosed |
| US-10787444-B2 | Compounds for the modulation of myc activity | SYROS PHARMACEUTICALS, INC. (US) | 2020-09-29 | — | — | US | disclosed |
| US-20180162851-A1 | COMPOUNDS FOR THE MODULATION OF MYC ACTIVITY | OXFORD FINANCE LLC, AS COLLATERAL AGENT | 2018-06-14 | — | — | US | disclosed |
| US-20180162851-A1 | COMPOUNDS FOR THE MODULATION OF MYC ACTIVITY | OXFORD FINANCE LLC, AS COLLATERAL AGENT | 2018-06-14 | — | — | US | disclosed |
| EP-2630196-B1 | CYANINE DYES AND THEIR CONJUGATES | LI COR INC (US) | 2017-09-06 | — | — | EP | disclosed |
| WO-2016197078-A1 | COMPOUNDS FOR THE MODULATION OF MYC ACTIVITY | SYROS PHARMACEUTICALS, INC. (US) | 2016-12-08 | — | — | WO | disclosed |
| US-9408924-B2 | Bioconjugates of cyanine dyes | LI-COR, INC. (US) | 2016-08-09 | — | — | US | disclosed |
| US-9248203-B2 | Fluorescent imaging with substituted cyanine dyes | LI-COR, INC. (US) | 2016-02-02 | — | — | US | disclosed |
| US-9089603-B2 | Fluorescent imaging with substituted cyanine dyes | LI-COR, INC. (US) | 2015-07-28 | — | — | US | disclosed |
| US-20150119553-A1 | BIOCONJUGATES OF CYANINE DYES | LI-COR, INC. | 2015-04-30 | — | — | US | disclosed |
| US-8927719-B2 | Cyanine dyes and their conjugates | LI-COR, INC. (US) | 2015-01-06 | — | — | US | disclosed |
| US-20140140962-A1 | VIRUSES MODIFIED WITH UNNATURAL MOIETIES AND METHODS OF USE THEREOF | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2014-05-22 | — | — | US | disclosed |
| US-20130280172-A1 | FLUORESCENT IMAGING WITH SUBSTITUTED CYANINE DYES | MIDCAP FINANCIAL TRUST | 2013-10-24 | — | — | US | disclosed |
| US-20130274452-A1 | CYANINE DYES AND THEIR CONJUGATES | MIDCAP FINANCIAL TRUST | 2013-10-17 | — | — | US | disclosed |
| US-20130039860-A1 | FLUORESCENT IMAGING WITH SUBSTITUTED CYANINE DYES | LI-COR, INC. (US) | 2013-02-14 | — | — | US | disclosed |
| US-7642059-B2 | A highly specific homogeneous assay using FKBP'in a single receptor format; immunophilin; rapamycin ; tacrolimus | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-20080299170-A1 | Medical Devices and Coatings Therefor | ASTON UNIVERSITY (GB) | 2008-12-04 | — | — | US | disclosed |
| US-20070054338-A1 | SINGLE RECEPTOR ASSAYS FOR IMMUNOSUPPRESSIVE DRUGS | SIGLER GERALD | 2007-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180162851-A1 | COMPOUNDS FOR THE MODULATION OF MYC ACTIVITY | MYC, MYCBP, MYCBP2 | KIF11 2413/4885KCNN4 650/4885DUT 3529/4885 |
| US-20080299170-A1 | Medical Devices and Coatings Therefor | F8, HABP2, TFPI | KIF11 3622/4885KCNN4 4726/4885DUT 2694/4885 |
| US-20130274452-A1 | CYANINE DYES AND THEIR CONJUGATES | FCGR3B, QPCT, TIE1 | KIF11 1799/4885KCNN4 3000/4885DUT 547/4885 |
| US-20210188833-A1 | COMPOUNDS FOR THE MODULATION OF MYC ACTIVITY | MYC, MYCBP, MYCBP2 | KIF11 2268/4885KCNN4 623/4885DUT 3802/4885 |
| US-20230144106-A1 | COMPOUNDS FOR THE MODULATION OF MYC ACTIVITY | MYC, MYCBP, MYCBP2 | KIF11 2268/4885KCNN4 623/4885DUT 3802/4885 |
| US-10787444-B2 | Compounds for the modulation of myc activity | MYC, MYCBP, MYCBP2 | KIF11 2413/4885KCNN4 650/4885DUT 3529/4885 |
| US-20130280172-A1 | FLUORESCENT IMAGING WITH SUBSTITUTED CYANINE DYES | TIE1, ALG1, MSR1 | KIF11 2146/4885KCNN4 1789/4885DUT 1020/4885 |
| US-20150119553-A1 | BIOCONJUGATES OF CYANINE DYES | FCGR3B, FCGR2A, HCCS | KIF11 2766/4885KCNN4 2454/4885DUT 1316/4885 |
| US-20130039860-A1 | FLUORESCENT IMAGING WITH SUBSTITUTED CYANINE DYES | TIE1, ALG1, MSR1 | KIF11 2146/4885KCNN4 1789/4885DUT 1020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.